Fullmetal Alchemist: Brotherhood

Alchemy: The science of understanding, deconstructing, and reconstructing matter. However, it is not an all-powerful art; it is impossible to create something out of nothing. If one wishes to obtain something, something of equal value must be given. This is the Law of Equivalent Exchange, the basis of all alchemy. In accordance with this law, there is a taboo among alchemists: human transmutation is strictly forbidden — for what could equal the value of a human soul...?

Quite possibly the best show ever made. FMAB lures you in with a well thought out world and a whole lot of intrigue. However, it quickly turns into a complex and profound meditation on brotherhood, loss, relentless determination, sin, redemption, the fight against a corrupt state, the pursuit of knowledge and the very concepts of truth and humanity themselves. Somehow all of this is contained in an action packed ride with  incredible pacing and an emotional and epic score.